6VHZ

Klebsiella oxytoca NpsA N-terminal subdomain in complex with anthranilyl-AMSN

6VHZ の概要

• エントリーDOI: 10.2210/pdb6vhz/pdb
• 分子名称: NpsA Adenylation Domain, 5'-{[(benzenecarbonyl)sulfamoyl]amino}-5'-deoxyadenosine, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: adenylation, tilivalline, tilimycin, nrps, nonribosomal peptide synthetase, biosynthetic protein
• 由来する生物種: Klebsiella oxytoca
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 89186.70

構造登録者

Kreitler, D.F.,Gulick, A.M. (登録日: 2020-01-10, 公開日: 2020-06-24, 最終更新日: 2023-10-11)

• 主引用文献: Alexander, E.M.,Kreitler, D.F.,Guidolin, V.,Hurben, A.K.,Drake, E.,Villalta, P.W.,Balbo, S.,Gulick, A.M.,Aldrich, C.C.; Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca.; Acs Infect Dis., 6:1976-1997, 2020; PubMed: 32485104; DOI: 10.1021/acsinfecdis.0c00326

実験手法

X-RAY DIFFRACTION (2.12 Å)