6VHL
Paired Helical Filament from Alzheimer's Disease Human Brain Tissue
Summary for 6VHL
Entry DOI | 10.2210/pdb6vhl/pdb |
EMDB information | 21207 |
Descriptor | Microtubule-associated protein tau, GLYCINE (2 entities in total) |
Functional Keywords | pathological amyloid fibril cross-beta fold parallel beta-sheets, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 17041.42 |
Authors | Arakhamia, T.,Lee, C.E.,Carlomagno, Y.,Duong, D.M.,Kundinger, S.R.,Wang, K.,Williams, D.,DeTure, M.,Dickson, D.W.,Cook, C.N.,Seyfried, N.T.,Petrucelli, L.,Fitzpatrick, A.W.P. (deposition date: 2020-01-10, release date: 2020-03-04, Last modification date: 2024-03-06) |
Primary citation | Arakhamia, T.,Lee, C.E.,Carlomagno, Y.,Duong, D.M.,Kundinger, S.R.,Wang, K.,Williams, D.,DeTure, M.,Dickson, D.W.,Cook, C.N.,Seyfried, N.T.,Petrucelli, L.,Fitzpatrick, A.W.P. Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell, 180:633-644.e12, 2020 Cited by PubMed: 32032505DOI: 10.1016/j.cell.2020.01.027 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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