6VHE

FphF, Staphylococcus aureus fluorophosphonate-binding serine hydrolases F, KT130 bound

6VHE の概要

• エントリーDOI: 10.2210/pdb6vhe/pdb
• 分子名称: Esterase family protein, (2~{R})-2-phenylpiperidine-1-carbaldehyde (3 entities in total)
• 機能のキーワード: fphf, fluorophosphonate-binding, serine hydrolases, sodium bound, acyl, kt130, intermediate, hydrolase
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 117580.30

構造登録者

Fellner, M.,Mace, P.D. (登録日: 2020-01-09, 公開日: 2020-09-16, 最終更新日: 2023-10-11)

• 主引用文献: Fellner, M.,Lentz, C.S.,Jamieson, S.A.,Brewster, J.L.,Chen, L.,Bogyo, M.,Mace, P.D.; Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus .; Acs Infect Dis., 6:2771-2782, 2020; PubMed: 32865965; DOI: 10.1021/acsinfecdis.0c00503

実験手法

X-RAY DIFFRACTION (1.94 Å)