6VG3

Structure of unliganded, inactive PTK7 kinase domain

Summary for 6VG3

• Entry DOI: 10.2210/pdb6vg3/pdb
• Descriptor: Inactive tyrosine-protein kinase 7 (2 entities in total)
• Functional Keywords: kinase, pseudokinase, autoinhibition, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 99851.99

Authors

Malhotra, K.,Stayrook, S.E.,Sheetz, J.,Lemmon, M.A. (deposition date: 2020-01-07, release date: 2020-05-27, Last modification date: 2023-10-11)

• Primary citation: Sheetz, J.B.,Mathea, S.,Karvonen, H.,Malhotra, K.,Chaterjee, D.,Perttila, R.,Niininen, W.,Stayrook, S.E.,Radhakrishnan, R.,Ungureanu, D.,Knapp, S.,Lemmon, M.A.; Structural insights into receptor tyrosine kinase pseudokinase function; Mol.Cell, 2020

Experimental method

X-RAY DIFFRACTION (1.95 Å)