6VFE

Gasdermin D pore

Summary for 6VFE

• Entry DOI: 10.2210/pdb6vfe/pdb
• EMDB information: 21160 21161
• Descriptor: Gasdermin-D, N-terminal (1 entity in total)
• Functional Keywords: pore-forming protein, lipid binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 33
• Total formula weight: 886057.29

Authors

Xia, S.,Ruan, J.,Wu, H. (deposition date: 2020-01-03, release date: 2021-04-21, Last modification date: 2024-05-29)

• Primary citation: Xia, S.,Zhang, Z.,Magupalli, V.G.,Pablo, J.L.,Dong, Y.,Vora, S.M.,Wang, L.,Fu, T.M.,Jacobson, M.P.,Greka, A.,Lieberman, J.,Ruan, J.,Wu, H.; Gasdermin D pore structure reveals preferential release of mature interleukin-1.; Nature, 593:607-611, 2021; PubMed: 33883744; DOI: 10.1038/s41586-021-03478-3

Experimental method

ELECTRON MICROSCOPY (3.9 Å)