6V9O
Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods
Summary for 6V9O
Entry DOI | 10.2210/pdb6v9o/pdb |
Descriptor | GTPase HRas, Son of sevenless homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (10 entities in total) |
Functional Keywords | ras, sos, inhibitor, oncoprotein, protein-protein complex, mapk, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 96048.72 |
Authors | Phan, J.,Fesik, S.W. (deposition date: 2019-12-13, release date: 2020-12-16, Last modification date: 2023-11-15) |
Primary citation | Phan, J.,Fesik, S.W. Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.799 Å) |
Structure validation
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