6V2U
Crystal structure of the insect cell-expressed WT-BRAF kinase in complex with Dabrafenib
Summary for 6V2U
Entry DOI | 10.2210/pdb6v2u/pdb |
Descriptor | Serine/threonine-protein kinase B-raf, Dabrafenib, CHLORIDE ION (3 entities in total) |
Functional Keywords | braf, mek1, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 65270.79 |
Authors | Li, K.,Gonzalez Del-Pino, G.,Park, E.,Eck, M.J. (deposition date: 2019-11-25, release date: 2020-12-02, Last modification date: 2023-10-11) |
Primary citation | Li, K.,Gonzalez Del-Pino, G.,Park, E.,Eck, M.J. Crystal structure of the insect cell-expressed WT-BRAF kinase in complex with Dabrafenib To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.78 Å) |
Structure validation
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