6V2U

Crystal structure of the insect cell-expressed WT-BRAF kinase in complex with Dabrafenib

Summary for 6V2U

• Entry DOI: 10.2210/pdb6v2u/pdb
• Descriptor: Serine/threonine-protein kinase B-raf, Dabrafenib, CHLORIDE ION (3 entities in total)
• Functional Keywords: braf, mek1, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 65270.79

Authors

Li, K.,Gonzalez Del-Pino, G.,Park, E.,Eck, M.J. (deposition date: 2019-11-25, release date: 2020-12-02, Last modification date: 2023-10-11)

• Primary citation: Li, K.,Gonzalez Del-Pino, G.,Park, E.,Eck, M.J.; Crystal structure of the insect cell-expressed WT-BRAF kinase in complex with Dabrafenib; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.78 Å)