6V0L

PDGFR-b Promoter Forms a G-Vacancy Quadruplex that Can be Complemented by dGMP: Molecular Structure and Recognition of Guanine Derivatives and Metabolites

6V0L の概要

• エントリーDOI: 10.2210/pdb6v0l/pdb
• NMR情報: BMRB: 30688
• 分子名称: DNA (5'-D(*(3D1)P*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*AP*CP*A)-3'), 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE (2 entities in total)
• 機能のキーワード: g-quadruplex, pdgfr-b, promoter, dna
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 6277.13

構造登録者

Wang, K.B.,Dickerhoff, J.,Wu, G.,Yang, D. (登録日: 2019-11-18, 公開日: 2020-03-11, 最終更新日: 2024-05-01)

• 主引用文献: Wang, K.B.,Dickerhoff, J.,Wu, G.,Yang, D.; PDGFR-beta Promoter Forms a Vacancy G-Quadruplex that Can Be Filled in by dGMP: Solution Structure and Molecular Recognition of Guanine Metabolites and Drugs.; J.Am.Chem.Soc., 142:5204-5211, 2020; PubMed: 32101424; DOI: 10.1021/jacs.9b12770

実験手法

SOLUTION NMR