6UYE
EBOV GPdMuc Makona bound to rEBOV-548 Fab
Summary for 6UYE
Entry DOI | 10.2210/pdb6uye/pdb |
EMDB information | 20947 |
Descriptor | SGP, Virion spike glycoprotein, Antibody rEBOV-548 Fab, heavy chain, ... (8 entities in total) |
Functional Keywords | antibody, ebola, synergy, cross-reactive, therapeutic, viral protein-immune system complex, viral protein/immune system |
Biological source | Ebola virus More |
Total number of polymer chains | 12 |
Total formula weight | 206398.84 |
Authors | Murin, C.D.,Ward, A.B. (deposition date: 2019-11-13, release date: 2020-03-11, Last modification date: 2020-07-29) |
Primary citation | Gilchuk, P.,Murin, C.D.,Milligan, J.C.,Cross, R.W.,Mire, C.E.,Ilinykh, P.A.,Huang, K.,Kuzmina, N.,Altman, P.X.,Hui, S.,Gunn, B.M.,Bryan, A.L.,Davidson, E.,Doranz, B.J.,Turner, H.L.,Alkutkar, T.,Flinko, R.,Orlandi, C.,Carnahan, R.,Nargi, R.,Bombardi, R.G.,Vodzak, M.E.,Li, S.,Okoli, A.,Ibeawuchi, M.,Ohiaeri, B.,Lewis, G.K.,Alter, G.,Bukreyev, A.,Saphire, E.O.,Geisbert, T.W.,Ward, A.B.,Crowe Jr., J.E. Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity, 52:388-403.e12, 2020 Cited by PubMed: 32023489DOI: 10.1016/j.immuni.2020.01.001 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.96 Å) |
Structure validation
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