6UXZ

(S)-4-Amino-5-phenoxypentanoate as a Selective Agonist of the Transcription Factor GabR

6UXZ の概要

• エントリーDOI: 10.2210/pdb6uxz/pdb
• 分子名称: HTH-type transcriptional regulatory protein GabR, SULFATE ION, (4S)-4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-5-phenoxypentanoic acid (3 entities in total)
• 機能のキーワード: gabr transcription factor, selective agonist gaba. metabolism, transcription
• 由来する生物種: Bacillus subtilis (strain 168)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 85269.11

構造登録者

Catlin, D.S.,Liu, D. (登録日: 2019-11-09, 公開日: 2020-10-07, 最終更新日: 2024-04-03)

• 主引用文献: Catlin, D.S.,Reidl, C.T.,Trzupek, T.R.,Silverman, R.B.,Cannon, B.L.,Becker, D.P.,Liu, D.; (S)-4-Amino-5-phenoxypentanoate designed as a potential selective agonist of the bacterial transcription factor GabR.; Protein Sci., 29:1816-1828, 2020; PubMed: 32557944; DOI: 10.1002/pro.3905

実験手法

X-RAY DIFFRACTION (2.8 Å)