6UWW

Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with P218 inhibitor

Summary for 6UWW

• Entry DOI: 10.2210/pdb6uww/pdb
• Descriptor: Dihydrofolate reductase, 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, SULFATE ION, ... (5 entities in total)
• Functional Keywords: ssgcid, dhfr, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase
• Biological source: Mycobacterium ulcerans (strain Agy99)
• Total number of polymer chains: 1
• Total formula weight: 20389.59

Authors

Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2019-11-05, release date: 2020-11-11, Last modification date: 2023-10-11)

• Primary citation: Mayclin, S.J.,Abendroth, J.A.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with SDDC-0001565 inhibitor; to be published,

Experimental method

X-RAY DIFFRACTION (0.92 Å)