6UWJ
Intermediate engineered variant of I-OnuI meganuclease with improved thermostability and partially altered specificity
6UWJ の概要
エントリーDOI | 10.2210/pdb6uwj/pdb |
分子名称 | I-OnuI-e-Therm-hChr11v2, DNA (27-MER), CALCIUM ION, ... (5 entities in total) |
機能のキーワード | meganuclease, homing endonuclease, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
由来する生物種 | synthetic construct 詳細 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 50898.78 |
構造登録者 | |
主引用文献 | Lambert, A.R.,Hallinan, J.P.,Werther, R.,Glow, D.,Stoddard, B.L. Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition. Structure, 28:760-775.e8, 2020 Cited by PubMed: 32359399DOI: 10.1016/j.str.2020.04.009 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.852 Å) |
構造検証レポート
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