6UUL

Crystal structure of broad and potent HIV-1 neutralizing antibody 438-D5

6UUL の概要

• エントリーDOI: 10.2210/pdb6uul/pdb
• 関連するPDBエントリー: 6UTK
• 分子名称: D5 Fab Heavy Chain, D5 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: v3 glycan supersite, human antibody, immune system, anti-hiv neutralizing antibody
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 98232.99

構造登録者

Kumar, S.,Wilson, I.A. (登録日: 2019-10-30, 公開日: 2020-09-23, 最終更新日: 2023-10-11)

• 主引用文献: Kumar, S.,Ju, B.,Shapero, B.,Lin, X.,Ren, L.,Zhang, L.,Li, D.,Zhou, Z.,Feng, Y.,Sou, C.,Mann, C.J.,Hao, Y.,Sarkar, A.,Hou, J.,Nunnally, C.,Hong, K.,Wang, S.,Ge, X.,Su, B.,Landais, E.,Sok, D.,Zwick, M.B.,He, L.,Zhu, J.,Wilson, I.A.,Shao, Y.; A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite.; Sci Adv, 6:-, 2020; PubMed: 32938661; DOI: 10.1126/sciadv.abb1328

実験手法