6USQ
Telomerase Reverse Transcriptase binary complex with Y256A mutation, TERT:DNA
Summary for 6USQ
Entry DOI | 10.2210/pdb6usq/pdb |
Descriptor | Telomerase reverse transcriptase, DNA (5'-D(*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*GP*GP*TP*CP*A)-3'), DNA/RNA (5'-R(*CP*UP*GP*AP*CP*CP*UP*GP*AP*C)-D(P*CP*T)-R(P*GP*AP*C)-D(P*C)-3'), ... (5 entities in total) |
Functional Keywords | telomerase, reverse transcriptase, polymerase, nuclear protein, transferase-rna-dna complex, transferase/rna/dna |
Biological source | Tribolium castaneum (Red flour beetle) More |
Total number of polymer chains | 3 |
Total formula weight | 80251.38 |
Authors | Schaich, M.A.,Freudenthal, B.D.,Khoang, T.H. (deposition date: 2019-10-28, release date: 2020-06-17, Last modification date: 2023-10-11) |
Primary citation | Schaich, M.A.,Sanford, S.L.,Welfer, G.A.,Johnson, S.A.,Khoang, T.H.,Opresko, P.L.,Freudenthal, B.D. Mechanisms of nucleotide selection by telomerase. Elife, 9:-, 2020 Cited by PubMed: 32501800DOI: 10.7554/eLife.55438 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.62 Å) |
Structure validation
Download full validation report