6UQK
Cryo-EM structure of type 3 IP3 receptor revealing presence of a self-binding peptide
Summary for 6UQK
Entry DOI | 10.2210/pdb6uqk/pdb |
EMDB information | 20849 |
Descriptor | inositol 1,4,5-triphosphate receptor, type 3, ZINC ION (2 entities in total) |
Functional Keywords | inositol trisphosphate receptor, insp3r, ip3r, cryoelectron microscopy, ion channel, calcium channel, isothermal titration calorimetry, self binding peptide, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 1114599.26 |
Authors | Azumaya, C.M.,Linton, E.A.,Risener, C.J.,Nakagawa, T.,Karakas, E. (deposition date: 2019-10-20, release date: 2020-01-15, Last modification date: 2024-03-20) |
Primary citation | Azumaya, C.M.,Linton, E.A.,Risener, C.J.,Nakagawa, T.,Karakas, E. Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist. J.Biol.Chem., 295:1743-1753, 2020 Cited by PubMed: 31915246DOI: 10.1074/jbc.RA119.011570 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.77 Å) |
Structure validation
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