6UMW
Crystal structure of hEphB1 bound with chlortetracycline
Summary for 6UMW
Entry DOI | 10.2210/pdb6umw/pdb |
Descriptor | Ephrin type-B receptor 1, 7-CHLOROTETRACYCLINE (3 entities in total) |
Functional Keywords | hephb1, chlortetracycline, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34848.06 |
Authors | |
Primary citation | Ahmed, M.S.,Wang, P.,Nguyen, N.U.N.,Nakada, Y.,Menendez-Montes, I.,Ismail, M.,Bachoo, R.,Henkemeyer, M.,Sadek, H.A.,Kandil, E.S. Identification of tetracycline combinations as EphB1 tyrosine kinase inhibitors for treatment of neuropathic pain. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33627480DOI: 10.1073/pnas.2016265118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.982 Å) |
Structure validation
Download full validation report