6ULS

BRD4-BD1 in complex with the a diacetylated-E2F1 peptide

Summary for 6ULS

• Entry DOI: 10.2210/pdb6uls/pdb
• Descriptor: Bromodomain-containing protein 4, Diacetylated E2F1 Peptide (K117ac and K120ac) (3 entities in total)
• Functional Keywords: bet, bromodomain, e2f1, brd4, acetylated, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 18246.83

Authors

Patel, K.,Low, J.K.K.,Mackay, J.P. (deposition date: 2019-10-08, release date: 2020-08-19, Last modification date: 2023-11-15)

• Primary citation: Patel, K.,Solomon, P.D.,Walshe, J.L.,Ford, D.J.,Wilkinson-White, L.,Payne, R.J.,Low, J.K.K.,Mackay, J.P.; BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism.; Biochemistry, 60:648-662, 2021; PubMed: 33620209; DOI: 10.1021/acs.biochem.0c00816

Experimental method

X-RAY DIFFRACTION (1.5 Å)