6UIA

Structure of ATP citrate lyase with CoA in a partially open conformation

Summary for 6UIA

Entry DOI	10.2210/pdb6uia/pdb
EMDB information	20784
Descriptor	ATP-citrate synthase, COENZYME A (2 entities in total)
Functional Keywords	open conformation, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	485471.63
Authors	Wei, X.,Marmorstein, R. (deposition date: 2019-09-30, release date: 2019-12-25, Last modification date: 2024-03-20)
Primary citation	Wei, X.,Schultz, K.,Bazilevsky, G.A.,Vogt, A.,Marmorstein, R. Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27:33-41, 2020 Cited by PubMed: 31873304 DOI: 10.1038/s41594-019-0351-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.3 Å)

Structure validation