6UGS

Crystal structure of the Fab fragment of PF06438179/GP1111 an infliximab biosimilar in a C-centered orthorhombic crystal form, Lot A

6UGS の概要

• エントリーDOI: 10.2210/pdb6ugs/pdb
• 分子名称: Infliximab (Remicade) Fab Heavy Chain, Infliximab (Remicade) Fab Light Chain (3 entities in total)
• 機能のキーワード: antibody, fab, infliximab, biosimilar, tnfa, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 95634.10

構造登録者

Lerch, T.F.,Sharpe, P.,Mayclin, S.J.,Edwards, T.E.,Polleck, S.,Rouse, J.C.,Conlan, H. (登録日: 2019-09-26, 公開日: 2019-11-13, 最終更新日: 2023-10-11)

• 主引用文献: Lerch, T.F.,Sharpe, P.,Mayclin, S.J.,Edwards, T.E.,Polleck, S.,Rouse, J.C.,Zou, Q.,Conlon, H.D.; Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.; BioDrugs, 34:77-87, 2020; PubMed: 31650490; DOI: 10.1007/s40259-019-00390-1

実験手法

X-RAY DIFFRACTION (1.95 Å)