6UER

Crystal form 2: Structure of TBP bound to C-C mismatch at pH 7

Summary for 6UER

• Entry DOI: 10.2210/pdb6uer/pdb
• Descriptor: TATA-box-binding protein 1, DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*CP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*CP*TP*TP*TP*AP*TP*AP*GP*C)-3'), ... (4 entities in total)
• Functional Keywords: tbp, tata box, transcription, mismatch site, ner, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Arabidopsis thaliana (Mouse-ear cress); More
• Total number of polymer chains: 6
• Total formula weight: 66070.49

Authors

Schumacher, M.A.,Al-Hashimi, H. (deposition date: 2019-09-22, release date: 2020-09-02, Last modification date: 2023-10-11)

• Primary citation: Afek, A.,Shi, H.,Rangadurai, A.,Sahay, H.,Senitzki, A.,Xhani, S.,Fang, M.,Salinas, R.,Mielko, Z.,Pufall, M.A.,Poon, G.M.K.,Haran, T.E.,Schumacher, M.A.,Al-Hashimi, H.M.,Gordan, R.; DNA mismatches reveal conformational penalties in protein-DNA recognition.; Nature, 587:291-296, 2020; PubMed: 33087930; DOI: 10.1038/s41586-020-2843-2

Experimental method

X-RAY DIFFRACTION (2.5 Å)