6UEG
Pseudomonas aeruginosa LpxA Complex Structure with Ligand
Summary for 6UEG
| Entry DOI | 10.2210/pdb6ueg/pdb |
| Descriptor | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, 3-({2-[(2R)-2-carbamoyl-2,3-dihydro-4H-1,4-benzoxazin-4-yl]-2-oxoethyl}sulfanyl)propanoic acid, CALCIUM ION, ... (4 entities in total) |
| Functional Keywords | lpxa, ligand complex, trimer, acyl transferase, transferase |
| Biological source | Pseudomonas aeruginosa (strain PA7) |
| Total number of polymer chains | 6 |
| Total formula weight | 170278.57 |
| Authors | Chen, Y.,Kroeck, K.,Sacco, M. (deposition date: 2019-09-20, release date: 2019-11-13, Last modification date: 2024-03-13) |
| Primary citation | Kroeck, K.G.,Sacco, M.D.,Smith, E.W.,Zhang, X.,Shoun, D.,Akhtar, A.,Darch, S.E.,Cohen, F.,Andrews, L.D.,Knox, J.E.,Chen, Y. Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography. Sci Rep, 9:15450-15450, 2019 Cited by PubMed: 31664082DOI: 10.1038/s41598-019-51844-z PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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