6U8P
Crystal structure of DNMT3B-DNMT3L in complex with CpGpA DNA
Summary for 6U8P
Entry DOI | 10.2210/pdb6u8p/pdb |
Descriptor | DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5)-methyltransferase 3-like, CpGpA DNA (25-MER), ... (6 entities in total) |
Functional Keywords | dnmt3b, dnmt3l, dna methylation, methyltransferase, transferase-dna complex, transferase, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 130915.61 |
Authors | |
Primary citation | Gao, L.,Emperle, M.,Guo, Y.,Grimm, S.A.,Ren, W.,Adam, S.,Uryu, H.,Zhang, Z.M.,Chen, D.,Yin, J.,Dukatz, M.,Anteneh, H.,Jurkowska, R.Z.,Lu, J.,Wang, Y.,Bashtrykov, P.,Wade, P.A.,Wang, G.G.,Jeltsch, A.,Song, J. Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11:3355-3355, 2020 Cited by PubMed: 32620778DOI: 10.1038/s41467-020-17109-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.05 Å) |
Structure validation
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