6U2M
Crystal structure of a HaloTag-based calcium indicator, HaloCaMP V2, bound to JF635
Summary for 6U2M
Entry DOI | 10.2210/pdb6u2m/pdb |
Descriptor | HaloCaMP V2, (1E,3S)-1-{10-[2-carboxy-5-({2-[2-(hexyloxy)ethoxy]ethyl}carbamoyl)phenyl]-7-(3-fluoroazetidin-1-yl)-5,5-dimethyldibenz o[b,e]silin-3(5H)-ylidene}-3-fluoroazetidin-1-ium, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | halotag, calcium, sensor, fluorescent, hydrolase |
Biological source | Rhodococcus sp. |
Total number of polymer chains | 2 |
Total formula weight | 113499.40 |
Authors | Deo, C.,Schreiter, E.R. (deposition date: 2019-08-20, release date: 2020-09-30, Last modification date: 2023-10-11) |
Primary citation | Deo, C.,Abdelfattah, A.S.,Bhargava, H.K.,Berro, A.J.,Falco, N.,Farrants, H.,Moeyaert, B.,Chupanova, M.,Lavis, L.D.,Schreiter, E.R. The HaloTag as a general scaffold for far-red tunable chemigenetic indicators. Nat.Chem.Biol., 17:718-723, 2021 Cited by PubMed: 33795886DOI: 10.1038/s41589-021-00775-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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