6U28
Crystal structure of 1918 NS1-ED W187A in complex with the p85-beta-iSH2 domain of human PI3K
Summary for 6U28
Entry DOI | 10.2210/pdb6u28/pdb |
Descriptor | Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta (2 entities in total) |
Functional Keywords | 1918 influenza a virus, ns1, pi3k, viral protein |
Biological source | Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) More |
Total number of polymer chains | 4 |
Total formula weight | 72462.63 |
Authors | Cho, J.H.,Zhao, B.,Savage, N.,Li, P. (deposition date: 2019-08-19, release date: 2020-04-22, Last modification date: 2023-10-11) |
Primary citation | Cho, J.H.,Zhao, B.,Shi, J.,Savage, N.,Shen, Q.,Byrnes, J.,Yang, L.,Hwang, W.,Li, P. Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses. Proc.Natl.Acad.Sci.USA, 117:6550-6558, 2020 Cited by PubMed: 32152123DOI: 10.1073/pnas.1920582117 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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