6U28

Crystal structure of 1918 NS1-ED W187A in complex with the p85-beta-iSH2 domain of human PI3K

Summary for 6U28

Entry DOI	10.2210/pdb6u28/pdb
Descriptor	Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta (2 entities in total)
Functional Keywords	1918 influenza a virus, ns1, pi3k, viral protein
Biological source	Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) More
Total number of polymer chains	4
Total formula weight	72462.63
Authors	Cho, J.H.,Zhao, B.,Savage, N.,Li, P. (deposition date: 2019-08-19, release date: 2020-04-22, Last modification date: 2023-10-11)
Primary citation	Cho, J.H.,Zhao, B.,Shi, J.,Savage, N.,Shen, Q.,Byrnes, J.,Yang, L.,Hwang, W.,Li, P. Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses. Proc.Natl.Acad.Sci.USA, 117:6550-6558, 2020 Cited by PubMed: 32152123 DOI: 10.1073/pnas.1920582117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation