6U22
Crystal structure of SFTI-triazole inhibitor in complex with beta-trypsin
Summary for 6U22
Entry DOI | 10.2210/pdb6u22/pdb |
Descriptor | Cationic trypsin, GLY-ARG-ALA-THR-LYS-SER-ILE-PRO-PRO-ILE-ALA-PHE-PRO-ASP, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | triazole, peptidomimetic, biosynthetic protein, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Bos taurus (Bovine) More |
Total number of polymer chains | 2 |
Total formula weight | 24919.16 |
Authors | White, A.M.,King, G.J.,Durek, T.,Craik, D.J. (deposition date: 2019-08-19, release date: 2020-07-01, Last modification date: 2023-10-11) |
Primary citation | White, A.M.,de Veer, S.J.,Wu, G.,Harvey, P.J.,Yap, K.,King, G.J.,Swedberg, J.E.,Wang, C.K.,Law, R.H.P.,Durek, T.,Craik, D.J. Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angew.Chem.Int.Ed.Engl., 59:11273-11277, 2020 Cited by PubMed: 32270580DOI: 10.1002/anie.202003435 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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