6U0K
TTBK2 kinase domain in complex with Compound 1
Summary for 6U0K
Entry DOI | 10.2210/pdb6u0k/pdb |
Descriptor | Tau-tubulin kinase 2, PHOSPHATE ION, 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, ... (5 entities in total) |
Functional Keywords | ttbk2, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 70446.05 |
Authors | Marcotte, D.J.,Chodaparambil, J.V. (deposition date: 2019-08-14, release date: 2020-03-11, Last modification date: 2023-10-11) |
Primary citation | Marcotte, D.J.,Spilker, K.A.,Wen, D.,Hesson, T.,Patterson, T.A.,Kumar, R.,Chodaparambil, J.V. The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small-molecule inhibitor Acta Crystallogr.,Sect.F, 76:103-108, 2020 Cited by DOI: 10.1107/S2053230X2000031XPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.744 Å) |
Structure validation
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