6TZV

Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis

6TZV の概要

• エントリーDOI: 10.2210/pdb6tzv/pdb
• 関連するPDBエントリー: 6PRW
• 分子名称: Probable propionyl-CoA carboxylase beta chain 6, 4'-[(6-chloro-1,3-benzothiazol-2-yl)oxy]-6-hydroxy-4,4-dimethyl-4,5-dihydro[1,1'-biphenyl]-2(3H)-one (3 entities in total)
• 機能のキーワード: transferase inhibitor accd6, carboxyltransferase beta-subunit of acyl-coacarboxylase, structural genomics, tb structural genomics consortium, tbsgc, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 404790.60

構造登録者

Reddy, M.C.M.,Zhou, N.,Sacchettini, J.,TB Structural Genomics Consortium (TBSGC) (登録日: 2019-08-13, 公開日: 2020-08-19, 最終更新日: 2024-03-13)

• 主引用文献: Reddy, M.C.M.,Zhou, N.,Sacchettini, J.; Novel herbicidal derivatives that inhibit carboxyltransferase subunit of the acetyl-CoA carboxylase in Mycobacterium tuberculosis; To Be Published,

実験手法

X-RAY DIFFRACTION (2.388 Å)