6TYS

A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection

Summary for 6TYS

• Entry DOI: 10.2210/pdb6tys/pdb
• EMDB information: 20584
• Descriptor: Fusion glycoprotein F0, 5B3 antibody heavy chain, 5B3 antibody light chain, ... (7 entities in total)
• Functional Keywords: henipavirus, nipah virus, hendra virus, fusion glycoprotein, antibody, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein-immune system complex, viral protein/immune system
• Biological source: Nipah virus; More
• Total number of polymer chains: 9
• Total formula weight: 261038.15

Authors

Dang, H.V.,Chan, Y.P.,Park, Y.J.,Snijder, J.,Da Silva, S.C.,Vu, B.,Yan, L.,Feng, Y.R.,Rockx, B.,Geisbert, T.,Mire, C.E.,Broder, C.B.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2019-08-09, release date: 2019-10-09, Last modification date: 2020-07-29)

• Primary citation: Dang, H.V.,Chan, Y.P.,Park, Y.J.,Snijder, J.,Da Silva, S.C.,Vu, B.,Yan, L.,Feng, Y.R.,Rockx, B.,Geisbert, T.W.,Mire, C.E.,Broder, C.C.,Veesler, D.; An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections.; Nat.Struct.Mol.Biol., 26:980-987, 2019; PubMed: 31570878; DOI: 10.1038/s41594-019-0308-9

Experimental method

ELECTRON MICROSCOPY (3.5 Å)