6TYS

A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection

6TYS の概要

• エントリーDOI: 10.2210/pdb6tys/pdb
• EMDBエントリー: 20584
• 分子名称: Fusion glycoprotein F0, 5B3 antibody heavy chain, 5B3 antibody light chain, ... (7 entities in total)
• 機能のキーワード: henipavirus, nipah virus, hendra virus, fusion glycoprotein, antibody, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Nipah virus; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 261038.15

構造登録者

Dang, H.V.,Chan, Y.P.,Park, Y.J.,Snijder, J.,Da Silva, S.C.,Vu, B.,Yan, L.,Feng, Y.R.,Rockx, B.,Geisbert, T.,Mire, C.E.,Broder, C.B.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2019-08-09, 公開日: 2019-10-09, 最終更新日: 2020-07-29)

• 主引用文献: Dang, H.V.,Chan, Y.P.,Park, Y.J.,Snijder, J.,Da Silva, S.C.,Vu, B.,Yan, L.,Feng, Y.R.,Rockx, B.,Geisbert, T.W.,Mire, C.E.,Broder, C.C.,Veesler, D.; An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections.; Nat.Struct.Mol.Biol., 26:980-987, 2019; PubMed: 31570878; DOI: 10.1038/s41594-019-0308-9

実験手法

ELECTRON MICROSCOPY (3.5 Å)