6TYB

Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields

6TYB の概要

• エントリーDOI: 10.2210/pdb6tyb/pdb
• 分子名称: Envelope glycoprotein gp160, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• 機能のキーワード: bnabs, gp120, fab, immune system, glycan
• 由来する生物種: Simian immunodeficiency virus (SIV); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 120509.04

構造登録者

Gorman, J.,Kwong, P.D. (登録日: 2019-08-08, 公開日: 2019-10-02, 最終更新日: 2023-10-11)

• 主引用文献: Gorman, J.,Mason, R.D.,Nettey, L.,Cavett, N.,Chuang, G.Y.,Peng, D.,Tsybovsky, Y.,Verardi, R.,Nguyen, R.,Ambrozak, D.,Biris, K.,LaBranche, C.C.,Ramesh, A.,Schramm, C.A.,Zhou, J.,Bailer, R.T.,Kepler, T.B.,Montefiori, D.C.,Shapiro, L.,Douek, D.C.,Mascola, J.R.,Roederer, M.,Kwong, P.D.; Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.; Immunity, 51:724-, 2019; PubMed: 31586542; DOI: 10.1016/j.immuni.2019.09.007

実験手法

X-RAY DIFFRACTION (2.301 Å)