6TXZ

FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3

Summary for 6TXZ

• Entry DOI: 10.2210/pdb6txz/pdb
• Descriptor: Hepatitis A virus cellular receptor 2, Fab H, Fab L (3 entities in total)
• Functional Keywords: fab, antibody, tim3, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 236808.41

Authors

Musil, D.,Sood, V. (deposition date: 2020-01-15, release date: 2020-04-08, Last modification date: 2024-01-24)

• Primary citation: Zhang, D.,Jiang, F.,Zaynagetdinov, R.,Huang, H.,Sood, V.D.,Wang, H.,Zhao, X.,Jenkins, M.H.,Ji, Q.,Wang, Y.,Nannemann, D.P.,Musil, D.,Wesolowski, J.,Paoletti, A.,Bartholomew, T.,Derner, M.G.,An, Q.,Iffland, C.,Halle, J.P.; Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody.; Oncoimmunology, 9:1744921-1744921, 2020; PubMed: 32313722; DOI: 10.1080/2162402X.2020.1744921

Experimental method

X-RAY DIFFRACTION (3.06 Å)