6TXP

Human Aldose Reductase Mutant L300A in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid)

6TXP の概要

• エントリーDOI: 10.2210/pdb6txp/pdb
• 分子名称: Aldo-keto reductase family 1 member B1, CITRIC ACID, 3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid, ... (6 entities in total)
• 機能のキーワード: oxidoreductase, l300a mutant, sar_061 ligand, har, opened and closed transient pocket
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37352.25

構造登録者

Hubert, L.-S.,Ley, M.,Heine, A.,Klebe, G. (登録日: 2020-01-14, 公開日: 2021-01-27, 最終更新日: 2024-01-24)

• 主引用文献: Hubert, L.-S.,Ley, M.,Scheer, F.,Diederich, W.,Heine, A.,Klebe, G.; Human Aldose Reductase Mutant L300A in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid); To Be Published,

実験手法

X-RAY DIFFRACTION (0.95 Å)