6TUV

Crystal structure of Mindy1 in complex with Lys48 linked di-ubiquitin

Summary for 6TUV

• Entry DOI: 10.2210/pdb6tuv/pdb
• Descriptor: Ubiquitin carboxyl-terminal hydrolase MINDY-1, Polyubiquitin-C, SULFATE ION, ... (4 entities in total)
• Functional Keywords: hydrolase, cysteine protease, isopeptidase and ubiquitin binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 57832.71

Authors

Abdul Rehman, S.A.,Kulathu, Y. (deposition date: 2020-01-08, release date: 2021-01-27, Last modification date: 2024-01-24)

• Primary citation: Abdul Rehman, S.A.,Armstrong, L.A.,Lange, S.M.,Kristariyanto, Y.A.,Grawert, T.W.,Knebel, A.,Svergun, D.I.,Kulathu, Y.; Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.; Mol.Cell, 81:4176-4190.e6, 2021; PubMed: 34529927; DOI: 10.1016/j.molcel.2021.08.024

Experimental method