6TQU

The crystal structure of the MSP domain of human MOSPD2 in complex with the Phospho-FFAT motif of STARD3.

Summary for 6TQU

Entry DOI	10.2210/pdb6tqu/pdb
Descriptor	Motile sperm domain-containing protein 2, StAR-related lipid transfer protein 3, SULFATE ION, ... (4 entities in total)
Functional Keywords	membrane contact sites, ffat motif, msp domain, endoplasmic reticulum, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	34630.84
Authors	McEwen, A.G.,Poussin-Courmontagne, P.,Di Mattia, T.,Wendling, C.,Cavarelli, J.,Tomasetto, C.,Alpy, F. (deposition date: 2019-12-17, release date: 2020-11-18, Last modification date: 2024-01-24)
Primary citation	Di Mattia, T.,Martinet, A.,Ikhlef, S.,McEwen, A.G.,Nomine, Y.,Wendling, C.,Poussin-Courmontagne, P.,Voilquin, L.,Eberling, P.,Ruffenach, F.,Cavarelli, J.,Slee, J.,Levine, T.P.,Drin, G.,Tomasetto, C.,Alpy, F. FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts. Embo J., 39:e104369-e104369, 2020 Cited by PubMed: 33124732 DOI: 10.15252/embj.2019104369 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation