6TQU

The crystal structure of the MSP domain of human MOSPD2 in complex with the Phospho-FFAT motif of STARD3.

6TQU の概要

• エントリーDOI: 10.2210/pdb6tqu/pdb
• 分子名称: Motile sperm domain-containing protein 2, StAR-related lipid transfer protein 3, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: membrane contact sites, ffat motif, msp domain, endoplasmic reticulum, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 34630.84

構造登録者

McEwen, A.G.,Poussin-Courmontagne, P.,Di Mattia, T.,Wendling, C.,Cavarelli, J.,Tomasetto, C.,Alpy, F. (登録日: 2019-12-17, 公開日: 2020-11-18, 最終更新日: 2024-01-24)

• 主引用文献: Di Mattia, T.,Martinet, A.,Ikhlef, S.,McEwen, A.G.,Nomine, Y.,Wendling, C.,Poussin-Courmontagne, P.,Voilquin, L.,Eberling, P.,Ruffenach, F.,Cavarelli, J.,Slee, J.,Levine, T.P.,Drin, G.,Tomasetto, C.,Alpy, F.; FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts.; Embo J., 39:e104369-e104369, 2020; PubMed: 33124732; DOI: 10.15252/embj.2019104369

実験手法

X-RAY DIFFRACTION (2.4 Å)