6TPR
PqsR (MvfR) bound to inhibitory compound 40
Summary for 6TPR
Entry DOI | 10.2210/pdb6tpr/pdb |
Descriptor | Transcriptional regulator MvfR, 2-[(5-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-~{N}-(4-pyridin-2-yloxyphenyl)ethanamide (3 entities in total) |
Functional Keywords | pseudomonas aeruginosa, quorum sensing, dna binding protein |
Biological source | Pseudomonas aeruginosa UCBPP-PA14 |
Total number of polymer chains | 1 |
Total formula weight | 27191.69 |
Authors | Richardson, W.K.,Emsley, J. (deposition date: 2019-12-14, release date: 2020-05-13, Last modification date: 2024-01-24) |
Primary citation | Soukarieh, F.,Liu, R.,Romero, M.,Roberston, S.N.,Richardson, W.,Lucanto, S.,Oton, E.V.,Qudus, N.R.,Mashabi, A.,Grossman, S.,Ali, S.,Sou, T.,Kukavica-Ibrulj, I.,Levesque, R.C.,Bergstrom, C.A.S.,Halliday, N.,Mistry, S.N.,Emsley, J.,Heeb, S.,Williams, P.,Camara, M.,Stocks, M.J. Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm GrownPseudomonas aeruginosa. Front Chem, 8:204-204, 2020 Cited by PubMed: 32432073DOI: 10.3389/fchem.2020.00204 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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