6TNH

Deoxyguanylosuccinate synthase (DgsS) quaternary structure with AMPPcP, dGMP, Asp, Magnesium at 2.21 Angstrom resolution

Summary for 6TNH

Entry DOI	10.2210/pdb6tnh/pdb
Descriptor	Adenylosuccinate synthetase, SULFATE ION, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ... (7 entities in total)
Functional Keywords	2, 6-diaminopurine, phage phivc8, synthetase, biosynthetic protein
Biological source	Vibrio phage phiVC8
Total number of polymer chains	2
Total formula weight	83537.12
Authors	Sleiman, D.,Loc'h, J.,Haouz, A.,Kaminski, P.A. (deposition date: 2019-12-08, release date: 2020-12-16, Last modification date: 2024-01-24)
Primary citation	Sleiman, D.,Garcia, P.S.,Lagune, M.,Loc'h, J.,Haouz, A.,Taib, N.,Rothlisberger, P.,Gribaldo, S.,Marliere, P.,Kaminski, P.A. A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes. Science, 372:516-520, 2021 Cited by PubMed: 33926955 DOI: 10.1126/science.abe6494 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.21 Å)

Structure validation