6TMS

Crystal structure of a de novo designed hexameric helical-bundle protein

Summary for 6TMS

Entry DOI	10.2210/pdb6tms/pdb
Descriptor	a novel designed pore protein, affinity purification tag, SULFATE ION, ... (5 entities in total)
Functional Keywords	helical bundle, hexamer, computational protein design, pore, de novo protein, biosynthetic protein
Biological source	synthetic construct More
Total number of polymer chains	14
Total formula weight	99280.63
Authors	Xu, C.,Pei, X.Y.,Luisi, B.F.,Baker, D. (deposition date: 2019-12-05, release date: 2020-04-29, Last modification date: 2024-05-01)
Primary citation	Xu, C.,Lu, P.,Gamal El-Din, T.M.,Pei, X.Y.,Johnson, M.C.,Uyeda, A.,Bick, M.J.,Xu, Q.,Jiang, D.,Bai, H.,Reggiano, G.,Hsia, Y.,Brunette, T.J.,Dou, J.,Ma, D.,Lynch, E.M.,Boyken, S.E.,Huang, P.S.,Stewart, L.,DiMaio, F.,Kollman, J.M.,Luisi, B.F.,Matsuura, T.,Catterall, W.A.,Baker, D. Computational design of transmembrane pores. Nature, 585:129-134, 2020 Cited by PubMed: 32848250 DOI: 10.1038/s41586-020-2646-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation