6TLO

HUMAN CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 4,5,6-TRIBROMOBENZOTRIAZOLE

6TLO の概要

• エントリーDOI: 10.2210/pdb6tlo/pdb
• 分子名称: Casein kinase II subunit alpha, 5,6,7-tris(bromanyl)-1~{H}-benzotriazole, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: ck2, casein kinase 2, inhibitor, bromo-benzotriazole, halogen bond, transferase-transferase inhibitor complex, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 47085.22

構造登録者

Czapinska, H.,Piasecka, A.,Winiewska-Szajewska, M.,Bochtler, M.,Poznanski, J. (登録日: 2019-12-03, 公開日: 2020-12-16, 最終更新日: 2024-01-24)

• 主引用文献: Czapinska, H.,Winiewska-Szajewska, M.,Szymaniec-Rutkowska, A.,Piasecka, A.,Bochtler, M.,Poznanski, J.; Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2.; J.Phys.Chem.B, 125:2491-2503, 2021; PubMed: 33689348; DOI: 10.1021/acs.jpcb.0c10264

実験手法

X-RAY DIFFRACTION (1.69 Å)