6TL6
Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide
Summary for 6TL6
Entry DOI | 10.2210/pdb6tl6/pdb |
Descriptor | Carbonic anhydrase 9, ZINC ION, naphthalene-2-sulfonamide, ... (5 entities in total) |
Functional Keywords | lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 114021.66 |
Authors | Leitans, J.,Tars, K. (deposition date: 2019-12-01, release date: 2020-12-16, Last modification date: 2024-01-24) |
Primary citation | Dudutiene, V.,Zubriene, A.,Kairys, V.,Smirnov, A.,Smirnoviene, J.,Leitans, J.,Kazaks, A.,Tars, K.,Manakova, L.,Grazulis, S.,Matulis, D. Isoform-Selective Enzyme Inhibitors by Exploring Pocket Size According to the Lock-and-Key Principle. Biophys.J., 119:1513-1524, 2020 Cited by PubMed: 32971003DOI: 10.1016/j.bpj.2020.08.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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