6TL2

Crystal structure of Eremococcus coleocola manganese transporter in complex with an aromatic bis-isothiourea substituted compound

6TL2 の概要

• エントリーDOI: 10.2210/pdb6tl2/pdb
• 分子名称: Divalent metal cation transporter MntH, [3-bromanyl-5-(carbamimidoylsulfanylmethyl)phenyl]methyl carbamimidothioate (2 entities in total)
• 機能のキーワード: inhibitor complex, transport protein
• 由来する生物種: Eremococcus coleocola ACS-139-V-Col8
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54031.47

構造登録者

Manatschal, C.,Dutzler, R. (登録日: 2019-11-29, 公開日: 2019-12-18, 最終更新日: 2024-01-24)

• 主引用文献: Manatschal, C.,Pujol-Gimenez, J.,Poirier, M.,Reymond, J.L.,Hediger, M.A.,Dutzler, R.; Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds.; Elife, 8:-, 2019; PubMed: 31804182; DOI: 10.7554/eLife.51913

実験手法

X-RAY DIFFRACTION (3.8 Å)