6TKY

Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42

Summary for 6TKY

• Entry DOI: 10.2210/pdb6tky/pdb
• Descriptor: Dedicator of cytokinesis protein 10, Cell division control protein 42 homolog, GLYCEROL, ... (5 entities in total)
• Functional Keywords: dock10 gef cdc42 gtpase, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 148302.43

Authors

Barford, D.,Fan, D.,Cronin, N.,Yang, J. (deposition date: 2019-11-29, release date: 2020-01-22, Last modification date: 2024-01-24)

• Primary citation: Fan, D.,Yang, J.,Cronin, N.,Barford, D.; Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10; Biorxiv, 2022; DOI: 10.1101/2022.06.15.496229

Experimental method

X-RAY DIFFRACTION (2.55 Å)