6TJK

Crystal Structure of Recombinant GBA in Complex with Bis-Tris Propane.

This is a non-PDB format compatible entry.

Summary for 6TJK

• Entry DOI: 10.2210/pdb6tjk/pdb
• Related: 6TJJ
• Descriptor: Lysosomal acid glucosylceramidase, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (7 entities in total)
• Functional Keywords: beta-glucocerebrosidase, lysosomal glycoside hydrolase, gh30, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 117673.65

Authors

Rowland, R.J.,Davies, G.J. (deposition date: 2019-11-26, release date: 2020-06-10, Last modification date: 2024-02-07)

• Primary citation: Rowland, R.J.,Wu, L.,Liu, F.,Davies, G.J.; A baculoviral system for the production of human beta-glucocerebrosidase enables atomic resolution analysis.; Acta Crystallogr D Struct Biol, 76:565-580, 2020; PubMed: 32496218; DOI: 10.1107/S205979832000501X

Experimental method

X-RAY DIFFRACTION (1.56 Å)