6TEZ

Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Val80Lys mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucuronic Acid

Summary for 6TEZ

Entry DOI	10.2210/pdb6tez/pdb
Descriptor	Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID, ... (9 entities in total)
Functional Keywords	collagen, lysyl hydroxylase, hydroxylysine, galactosyltransferase, glucosyltransferase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	84537.27
Authors	Chiapparino, A.,De Giorgi, F.,Scietti, L.,Faravelli, S.,Roscioli, T.,Forneris, F. (deposition date: 2019-11-12, release date: 2021-05-19, Last modification date: 2024-11-06)
Primary citation	Mattoteia, D.,Chiapparino, A.,Fumagalli, M.,De Marco, M.,De Giorgi, F.,Negro, L.,Pinnola, A.,Faravelli, S.,Roscioli, T.,Scietti, L.,Forneris, F. Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity Int J Mol Sci, 2023 Cited by DOI: 10.3390/ijms241311213 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation