6TD0
Crystal structure of vaborbactam bound to KPC-2
Summary for 6TD0
Entry DOI | 10.2210/pdb6td0/pdb |
Descriptor | Carbapenem-hydrolyzing beta-lactamase KPC, Vaborbactam, GLYCEROL, ... (5 entities in total) |
Functional Keywords | inhibitor, boronate, beta-lactamase, antimicrobial protein |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 31768.27 |
Authors | Tooke, C.L.,Hinchliffe, P.,Spencer, J. (deposition date: 2019-11-07, release date: 2020-01-22, Last modification date: 2024-01-24) |
Primary citation | Tooke, C.L.,Hinchliffe, P.,Krajnc, A.,Mulholland, A.J.,Brem, J.,Schofield, C.J.,Spencer, J. Cyclic boronates as versatile scaffolds for KPC-2 beta-lactamase inhibition. Rsc Med Chem, 11:491-496, 2020 Cited by PubMed: 33479650DOI: 10.1039/c9md00557a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.99 Å) |
Structure validation
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