6TCV

Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 in complex with Man9GlcNAc2Asn substrate

Summary for 6TCV

• Entry DOI: 10.2210/pdb6tcv/pdb
• Descriptor: Endo-beta-N-acetylglucosaminidase F1, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARAGINE, ... (5 entities in total)
• Functional Keywords: endo-b-n-acetylglucosaminidase, endobt, glycoside hydrolase, hydrolase
• Biological source: Bacteroides thetaiotaomicron VPI-5482
• Total number of polymer chains: 1
• Total formula weight: 51241.66

Authors

Trastoy, B.,Du, J.J.,Klontz, E.H.,Cifuente, J.O.,Sundberg, E.J.,Guerin, M.E. (deposition date: 2019-11-06, release date: 2020-02-26, Last modification date: 2024-01-24)

• Primary citation: Trastoy, B.,Du, J.J.,Klontz, E.H.,Li, C.,Cifuente, J.O.,Wang, L.X.,Sundberg, E.J.,Guerin, M.E.; Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides.; Nat Commun, 11:899-899, 2020; PubMed: 32060313; DOI: 10.1038/s41467-020-14754-7

Experimental method

X-RAY DIFFRACTION (1.311 Å)