6TCE
Crystal structure of the GGCT site-bound MH1 domain of Smad5 containing a GGGS insertion in the Loop1
Summary for 6TCE
Entry DOI | 10.2210/pdb6tce/pdb |
Related | 6FZS 6tbz |
Descriptor | Mothers against decapentaplegic homolog 5, DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP*A)-3'), ZINC ION (3 entities in total) |
Functional Keywords | tgf-b, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 20177.26 |
Authors | Pluta, R.,Macias, M.J. (deposition date: 2019-11-05, release date: 2019-11-20, Last modification date: 2024-01-24) |
Primary citation | Ruiz, L.,Kaczmarska, Z.,Gomes, T.,Aragon, E.,Torner, C.,Freier, R.,Baginski, B.,Martin-Malpartida, P.,de Martin Garrido, N.,Marquez, J.A.,Cordeiro, T.N.,Pluta, R.,Macias, M.J. Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes. Comput Struct Biotechnol J, 19:632-646, 2021 Cited by PubMed: 33510867DOI: 10.1016/j.csbj.2020.12.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.92 Å) |
Structure validation
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