6T9R

Aplysia californica AChBP in complex with a cytisine derivative

This is a non-PDB format compatible entry.

Summary for 6T9R

• Entry DOI: 10.2210/pdb6t9r/pdb
• Descriptor: Acetylcholine binding protein, (1~{R},9~{S})-5-(3-oxidanylpropyl)-7,11-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4-dien-6-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: acetylcholine binding protein, nicotinic receptor surrogate, hydrolase
• Biological source: Aplysia californica (California sea hare)
• Total number of polymer chains: 10
• Total formula weight: 293433.86

Authors

Davis, S.,Hunter, W.N. (deposition date: 2019-10-28, release date: 2020-02-12, Last modification date: 2024-01-24)

• Primary citation: Davis, S.,Rego Campello, H.,Gallagher, T.,Hunter, W.N.; The thermodynamic profile and molecular interactions of a C(9)-cytisine derivative-binding acetylcholine-binding protein from Aplysia californica.; Acta Crystallogr.,Sect.F, 76:74-80, 2020; PubMed: 32039888; DOI: 10.1107/S2053230X20001168

Experimental method

X-RAY DIFFRACTION (1.72 Å)