6T3P

Human Aldose Reductase Mutant L300A in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)

Summary for 6T3P

• Entry DOI: 10.2210/pdb6t3p/pdb
• Descriptor: Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid, ... (5 entities in total)
• Functional Keywords: oxidoreductase, l300a mutant, complex with idd, opened transient binding pocket
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 37488.36

Authors

Hubert, L.-S.,Ley, M.,Heine, A.,Klebe, G. (deposition date: 2019-10-11, release date: 2020-11-18, Last modification date: 2024-01-24)

• Primary citation: Hubert, L.-S.,Ley, M.,Scheer, F.,Diederich, W.,Heine, A.,Klebe, G.; Human Aldose Reductase Mutant L300A in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid); To Be Published,

Experimental method

X-RAY DIFFRACTION (0.97 Å)